Norepinephrine vs epinephrine: what's the difference? Read and carefully follow any Instructions for Use provided with your medicine. Generic Name: epinephrine injection (EP i NEF rin)Brand Name: Adrenalin, Auvi-Q, Epinephrinesnap-EMS, Epinephrinesnap-V, EpiPen 2-Pak, EpiPen JR 2-Pak, EPIsnap, SymjepiDosage Forms: injectable kit (0.1 mg; 0.15 mg; 0.3 mg; 1 mg/mL); injectable solution (0.1 mg/mL; 1 mg/250 mL-D5%; 1 mg/mL; 1 mg/mL preservative/sulfite-free; 10 mcg/mL-D5%; 16 mcg/mL-NaCl 0.9%; 2 mg/250 mL-D5%; 4 mg/250 mL-NaCl 0.9%); intravenous solution (10 mcg/mL-0.9%; 100 mcg/mL-NaCl 0.9%; 16 mcg/mL-D5%; 5 mg/250 mL-NaCl 0.9%), Medically reviewed by Drugs.com on Jul 8, 2020 – Written by Cerner Multum. Epinephrine is also used to treat exercise-induced anaphylaxis, or to treat low blood pressure that is caused by septic shock. Do not remove the safety cap until you are ready to use the auto-injector. If the needle is bent from the first use, it may cause serious injury to your skin. People who have never been stung may have an allergy without knowing it…, Certain situations will trigger an adrenaline rush, which is the release of adrenaline from the adrenal gland. Inhaled epinephrine may be used to improve the symptoms of croup. Epinephrine injection, USP auto-injector should only be injected into the middle of your outer thigh (upper leg). It is also used to treat anaphylaxis caused by unknown substances or triggered by exercise. Having an allergic reaction while pregnant or nursing could harm both mother and baby. Do not try to reinsert an auto-injector a second time if the needle has come out of your skin before the full 10 seconds. It is important to check the epinephrine auto-injector regularly and replace it with a new one if: However, in an emergency, it is better to give an out-of-date epinephrine injection than to give none at all. Usual Adult Dose for Asystole. The needle cap on the SYMJEPI prefilled syringe helps to prevent needle sticks and accidental injection of epinephrine. IM injection video 4. Call your doctor for medical advice about side effects. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine. Epinephrine injection may also be used for purposes not listed in this medication guide. Epinephrine, also known as adrenaline, is a medication and hormone. Epinephrine is released during acute stress and is associated with the fight-or-flight response. Inject only into the muscle of the outer thigh, never into a vein. Place the tip against the fleshy portion of the outer thigh. SYMJEPI can be injected through your clothing if needed. Inject the medicine into the fleshy outer portion of the thigh. Epinephrine is a life saving treatment for severe allergic reactions. You may repeat the injection every 5 … Use sharps disposal. Also seek emergency medical attention if you accidentally inject yourself while giving epinephrine to another person. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 2. What to know about epinephrine and norepinephrine. Make sure that family members understand how to administer this medication. Do not use solutions that are pinkish to brownish in color, cloudy, or contain a precipitate or particulate matter. Hold the auto-injector in place for 10 seconds after activation. It is only available with a prescription. Store at room temperature away from moisture, heat, and light. Call your doctor for medical advice about side effects. Epinephrine Auto-Injector and Prefilled Syringe. Failure to treat anaphylaxis increases the risk of death. For people with a bee sting allergy, the summer months can be a scary time. Many people refer to this device by the brand name EpiPen. Hold in place for 10 seconds. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Learn more about epinephrine’s production and effects. Store the device at room temperature and keep it away from light and heat. Press the device firmly into the thigh so that the needle can administer the epinephrine dose. There is no set dose for epinephrine — it is an emergency treatment that people should use as necessary. Store at controlled room temperature, below 25°C (77°F). Anyone who has any queries or concerns should speak to their doctor. People should tell their doctor about any medications or supplements that they are taking. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. After use, place the auto-injector into the tube (ensuring that the tip is pointing downward) and put the cap back on. What happens when you get an adrenaline rush? Do not use epinephrine injection if it has changed colors or has particles in it, or if the expiration date on the label has passed. Call your doctor at once if you notice pain, swelling, warmth, redness, or other signs of infection around the area where you gave an injection. EpiPen ® (epinephrine injection, USP) 0.3 mg or EpiPen Jr (epinephrine injection, USP) 0.15 mg Auto-Injectors are for the emergency treatment of life-threatening allergic reactions (anaphylaxis) caused by allergens, exercise, or unknown triggers; and for people who are at increased risk for these reactions. Epinephrine injection is used along with emergency medical treatment to treat life-threatening allergic reactions caused by insect bites or stings, foods, medications, latex, and other causes. The effects of epinephrine may wear off after 10 or 20 minutes. Epinephrine injection, USP auto-injector contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). the color changes or the liquid becomes cloudy. Do not give this medicine to a child without medical advice. In March 2020, the Food and Drug Administration (FDA) released a safety alert to warn the public that epinephrine auto-injectors (EpiPen, EpiPen Jr., and generic forms) may malfunction. Remove the auto-injector from the thigh and massage the area gently. Inject Adrenalin intramuscularly or subcutaneously into the anterolateral aspect of the thigh. It works by relaxing the muscles in the airways and tightening the blood vessels. Anaphylaxis is a life threatening allergic reaction that can occur within minutes of exposure to an allergen. Sometimes, people require a second dose or another follow-up treatment. 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